In collaboration with the labs of Raj Rohatgi and Andres Lebensohn, we investigated the mechanism of LGR independent Wnt signaling potentiation by R-spondin. The results of this study have now been published in Elife: “R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling.” Check out the publication here.
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Paper on R-spondin signaling
In collaboration with the labs of Raj Rohatgi and Andres Lebensohn, we investigated the mechanism of LGR independent Wnt signaling potentiation by R-spondin.