Author: Anton

The Maurice lab is proud to announce that Laigo Bio has launched their website!

Madelon is the co-founder and scientific lead of this startup that aims to develop SureTACs technology. Laigo Bio sprouted from the research of the Maurice lab, focused on degradation of target proteins at the cell surface, via redirection of transmembrane E3 ligases. How the induced proximity between target and E3 leads to ubiquitination, endocytosis and degradation of the target is actively being researched within the group.

Laigo Bio is dedicated to developing first-in-class therapeutics for patients with severe or life-threatening diseases by removing and degrading any cell surface targets with precision. Visit the website to learn how Laigo Bio is pioneering life-changing solutions in biotechnology: www.laigobio.com.

SureTACs (Surface Removal Targeting Chimeras) are heterobispecific molecules that target undesired cell surface proteins for degradation. The project is a collaboration of our lab at UMCU with Oncode and Laigo Bio.

Oncode Investigator @MadelonMaurice (@UMCUtrecht) received funding from @kwf_nl and @HealthHolland to further study the innovative SureTAC technology, designed in collaboration with @argobio and Oncode to break down cancer-specific proteins. Read more: https://t.co/UVV2qtfFTY pic.twitter.com/dUCKSoOpDY

— Oncode Institute (@oncodeinstitute) July 28, 2022

https://www.umcutrecht.nl/nl/over-ons/nieuws/algemeen/grote-subsidies-voor-publiek-privaat-kankeronderzoek

https://www.oncode.nl/news/oncode-investigator-madelon-maurice-receives-kwf-funding-for-innovative-suretac-technology

https://www.kwf.nl/onderzoek/dit-onderzoek-maken-we-mogelijk/PPS-toekenningen-2022-1

On the 8^th and 9^th of June, the Maurice lab went on a lab retreat in the beautiful surroundings of Gun located in Limburg. We stayed at an old farm where we spend two days talking about science, getting to know each other better and doing fun activities. We made a nice overview of all the projects within the lab and brainstormed about new future projects. We also learned a lot during the workshops that were given by our colleagues about sustainability, computational analysis and entrepreneurship. Finally we had a lot of fun during the pubquiz, karaoke and treasure hunt.