SureTACs (Surface Removal Targeting Chimeras) are heterobispecific molecules that target undesired cell surface proteins for degradation. The project is a collaboration of our lab at UMCU with Oncode and Laigo Bio.
https://www.kwf.nl/onderzoek/dit-onderzoek-maken-we-mogelijk/PPS-toekenningen-2022-1
On the 8th and 9th of June, the Maurice lab went on a lab retreat in the beautiful surroundings of Gun located in Limburg. We stayed at an old farm where we spend two days talking about science, getting to know each other better and doing fun activities. We made a nice overview of all the projects within the lab and brainstormed about new future projects. We also learned a lot during the workshops that were given by our colleagues about sustainability, computational analysis and entrepreneurship. Finally we had a lot of fun during the pubquiz, karaoke and treasure hunt.
In August 2019, our group published a new paper in Open Biology on single molecule FISH in organoids. Read this new publication here.
In January 2019, our group published on VHHs targeting LRP5/6 in Nature Communications. Check this new publication here.
In April 2018, our new paper on the role of TMEM59 in the Wnt signaling pathway was published. Check this new publication here.